Tumult has released Hype (http://tumultco.com/hype), a HTML5 animation builder for Mac OS X. Animations and interactive content made with Hype work on desktops, smartphones and iPads with no coding required.
Hype sports a keyframe-based animation system. It leverages a recording system to create effective motions and transition, according to the folks at Tumult.
Hype is available from the Mac App Store for an introductory price of $29.99. It requires Mac OS X 10.6 or higher.