The Alchemist Guild has released Warehouse 1.0 (http://www.warehouseosx.com), a task-based backup solution for Mac OS X. The US$9.99 offers a lightweight single window interface for backing up files from your Mac to any removable media device such as external hard drives, USB memory sticks or even other Macs connected on a network.
Warehouse uses a task based system that lets you create an unlimited number of tasks each with source folders, destination location and an option of four backup modes. It lets you schedule tasks to run in the background (using a variety of scheduling options) so the application itself can usually remain closed while it backs up files while you work.
Like TimeMachine, dated folders containing only changed files are incrementally backed up thus saving disk space. If you want to restore old archives browse them like other folders in the Finder and copy out files you want restored.
With Warehouse, you synchronize the contents of two folders on any destination by transferring only newer files to each destination. The core of the software uses UNIX utilities. Warehouse requires Mac with 10.5 or higher.